Create amino acid variability matrix from alignment of protein sequences
This tool computes ΔΔG and k* from an alignment of protein sequences and compiles a table with all the data. Additionally, it adds a parameter that measures the involvement
of each residue in contacts relevant for the protein's structure, if the couplings computed by EVFold or EVCouplings are provided.
Paste your alignment and optionally your coevolution data below and click Run.
The output table contains one row for each residue in the first sequence of the alignment. There are 24 columns: residue name, residue number, 20 columns with DDG values for all amino acids, k* value, and coevolution involvement if EVCouplings data was provided.